Glandular odontogenic cyst: a challenge in diagnosis and treatment

The present review analyzes the accumulated data from all cases of glandular odontogenic cyst (GOC) reported in the English language literature. In the 20 years since it was first described, 111 cases have been reported, an incidence of 0.2% of odontogenic cysts. The age range is 14–75, mean 45.7, w...

Full description

Saved in:
Bibliographic Details
Published in:Oral diseases 2008-10, Vol.14 (7), p.575-581
Main Authors: Kaplan, I, Anavi, Y, Hirshberg, A
Format: Article
Language:English
Subjects:
cyst
Dentistry
Diagnosis, Differential
glandular
Humans
Jaw Cysts - pathology
Jaw Cysts - surgery
jaws
odontogenic
Odontogenic Cysts - pathology
Odontogenic Cysts - surgery
Periodontal Cyst - pathology
Salivary Gland Diseases - pathology
Salivary Gland Diseases - surgery
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The present review analyzes the accumulated data from all cases of glandular odontogenic cyst (GOC) reported in the English language literature. In the 20 years since it was first described, 111 cases have been reported, an incidence of 0.2% of odontogenic cysts. The age range is 14–75, mean 45.7, with a M/F ratio of 1.3:1. GOC has a predilection for the mandible (70%), affecting both anterior and posterior areas. It is typically radiolucent, well defined, either unilocular (53.8%) or multilocular (46.2%). Frequent perforation (61%) and of thinning of cortical plates (24.4%) indicate aggressiveness. Sufficient follow‐up indicates that 30% of cases can recur. Treatment by enucleation or curettage carries the highest risk for recurrence, especially in large and multilocular lesions. Peripheral osteoectomy or marginal resection can eliminate the risk. Defined criteria for microscopic diagnosis are described, which in addition to Ki67 and p53 can help in differentiating GOC from lesions with histological similarities (cysts with mucous metaplasia, botryoid and surgical ciliated cysts, low‐grade mucoepidermoid carcinoma). Definite diagnosis may not be possible in small incisional biopsies due to the focal presentation of characteristic features required for diagnosis. There is now evidence to support an odontogenic rather than a sialogenic origin.
ISSN:1354-523X
1601-0825
DOI:10.1111/j.1601-0825.2007.01428.x