Cloacogenic Adenocarcinoma of the Vulva

Primary adenocarcinoma of the vulva is rare, and cloagocenic adenocarcinoma of the vulva is extremely rare. Here we report a vulvar tumor characterized by columnar cells with prominent brush border and the presence of goblet cells and endocrine cells, presenting the tubulovillous pattern and mucin h...

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Bibliographic Details
Published in:Gynecologic oncology 1999-08, Vol.74 (2), p.298-301
Main Authors: Willén, Roger, Békássy, Zoltan, Carlén, Birgitta, Bozoky, Bela, Cajander, Stefan
Format: Article
Language:English
Subjects:
Adenocarcinoma - pathology
Biological and medical sciences
Cloaca
cloacogenic carcinoma
Female
Female genital diseases
Gynecology. Andrology. Obstetrics
histopathology
Humans
immunopathology
Medical sciences
Middle Aged
Tumors
ultrastructure
vulva
Vulvar Neoplasms - pathology
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Summary:Primary adenocarcinoma of the vulva is rare, and cloagocenic adenocarcinoma of the vulva is extremely rare. Here we report a vulvar tumor characterized by columnar cells with prominent brush border and the presence of goblet cells and endocrine cells, presenting the tubulovillous pattern and mucin histochemistry of enteric adenocarcinoma. Electron microscopy verified a colon-like pattern. We suggest that cloacogenic carcinoma of the vulva arises from embryonic tissue, normally present in the vulvar introital area. In our case, a wide local excision was sufficient for radical cure.
ISSN:0090-8258
1095-6859
DOI:10.1006/gyno.1999.5433