The effect of cetylpyridinium chloride-containing mouth rinses as adjuncts to toothbrushing on plaque and parameters of gingival inflammation: a systematic review

:  Objective:  To review the literature concerning cetylpyridinium chloride (CPC) containing mouth rinses as effective adjuncts to toothbrushing in the prevention of plaque accumulation and gingival inflammation. Materials and methods:  Medline and the Cochrane Central Register of Controlled Trials...

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Bibliographic Details
Published in:International journal of dental hygiene 2008-11, Vol.6 (4), p.290-303
Main Authors: Haps, S, Slot, DE, Berchier, CE, Van der Weijden, GA
Format: Article
Language:English
Subjects:
Anti-Infective Agents, Local - therapeutic use
Biological and medical sciences
bleeding
Cetylpyridinium - therapeutic use
cetylpyridinium chloride
cetylpyridinium chloride mouth rinse
Dental care
Dental health
Dental Plaque - prevention & control
Dental Plaque Index
Dentistry
Effectiveness studies
Facial bones, jaws, teeth, parodontium: diseases, semeiology
gingivitis
Gingivitis - prevention & control
Gum disease
Health & beauty aids
Humans
Medical sciences
mouthwash
Mouthwashes - therapeutic use
Non tumoral diseases
Oral hygiene
Otorhinolaryngology. Stomatology
Periodontal Index
plaque
Randomized Controlled Trials as Topic
Research Design
Smoking
systematic review
Toothbrushing - methods
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Summary::  Objective:  To review the literature concerning cetylpyridinium chloride (CPC) containing mouth rinses as effective adjuncts to toothbrushing in the prevention of plaque accumulation and gingival inflammation. Materials and methods:  Medline and the Cochrane Central Register of Controlled Trials were searched up to January 2008 to identify appropriate studies. The primary outcome measurements were plaque accumulation and gingivitis. Results:  Independent screening of titles and s of 3250 papers resulted in eight publications that met the criteria of eligibility. Mean values and standard deviations were obtained by data extraction. Descriptive comparisons are presented for brushing only or brushing and rinsing. Meta‐analyses were performed when possible. Conclusions:  The existing evidence supports that CPC containing mouth rinses, when used as adjuncts to either supervised or unsupervised oral hygiene, provide a small but significant additional benefit in reducing plaque accumulation and gingival inflammation.
ISSN:1601-5029
1601-5037
DOI:10.1111/j.1601-5037.2008.00344.x