Six-Year Outcome for Cognitive Behavioral Treatment of Residual Symptoms in Major Depression

Objective:The authors' goal was to determine whether cognitive behavioral treatment of residual symptoms of depression might have a significant effect on relapse rate. Method:A 6-year follow-up assessment was conducted of 40 patients with primary major depressive disorder who had been successfu...

Full description

Saved in:
Bibliographic Details
Published in:The American journal of psychiatry 1998-10, Vol.155 (10), p.1443-1445
Main Authors: Fava, Giovanni A., Rafanelli, Chiara, Grandi, Silvana, Canestrari, Renzo, Morphy, Murray A.
Format: Article
Language:English
Subjects:
Adult
Behavior
Behavior therapy. Cognitive therapy
Biological and medical sciences
Clinical outcomes
Cognition & reasoning
Cognitive behaviour therapy
Cognitive Therapy
Depression
Depressive Disorder - prevention & control
Depressive Disorder - psychology
Depressive Disorder - therapy
Female
Follow-Up Studies
Followup studies
Humans
Italy
Male
Medical sciences
Mental depression
Middle Aged
Outcomes
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Residual symptoms
Secondary Prevention
Survival Analysis
Therapy
Treatment Outcome
Treatments
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective:The authors' goal was to determine whether cognitive behavioral treatment of residual symptoms of depression might have a significant effect on relapse rate. Method:A 6-year follow-up assessment was conducted of 40 patients with primary major depressive disorder who had been successfully treated with antidepressants and were randomly assigned to either cognitive behavioral treatment of residual symptoms or standard clinical management.Results:Ten of the patients (50%) in the cognitive behavioral treatment group and 15 (75%) in the standard clinical management group relapsed. The difference did not attain statistical significance. When multiple relapses were considered, patients in the cognitive behavioral treatment group had a significantly lower number of depressive episodes than those in the standard clinical management group. Patients responded to the same antidepressant drug used in the index episode; in two cases (4%), resistance occurred.Conclusions:The protective effects of cognitive behavioral treatment that were evident at 4-year follow-up faded afterward. Cognitive behavioral treatment of residual symptoms, however, improved the long-term outcome of major depression in terms of total number of episodes during the follow-up period. Am J Psychiatry 1998; 155: 1443-1445
ISSN:0002-953X
1535-7228
DOI:10.1176/ajp.155.10.1443