Sesquiterpene lactone glycosides from Lapsana communis L. subsp. communis

• Published in: Phytochemistry (Oxford) 1999-08, Vol.51 (8), p.999-1004
• Main Authors: Fontanel, Didier, Galtier, Christophe, Debouzy, Jean-Claude, Gueiffier, Alain, Viel, Claude
• Format: Article
• Language: English
• Subjects: Animals; Asteraceae; Asteraceae - chemistry; Biological and medical sciences; chemical constituents of plants; Chemical constitution; chemical structure; communis; Drug Screening Assays, Antitumor; Fundamental and applied biological sciences. Psychology; glycosides; Glycosides - chemistry; Glycosides - isolation & purification; Glycosides - pharmacology; Guaianolides; Lactones - chemistry; Lactuceae; Lapsana communis; latex; Leukemia L1210 - pathology; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; nuclear magnetic resonance spectroscopy; Plant physiology and development; Sesquiterpene lactone glycosides; Sesquiterpenes - chemistry; sesquiterpenoid lactones; spectral analysis
• ISSN: 0031-9422; 1873-3700
• DOI: 10.1016/S0031-9422(98)00718-3

From the latex of Lapsana communis L. subps. communis, five guaianolide glycosides were identified: crepiside E, tectoroside and three new ones: 3- O-P- d-glucopyranosyl-8- O-P-acetyl-1aH,5aH,6PH,7aH-guai-4 (15),10 (14),11 (13)-triene-6,12-olide, 3- O-P- d-glucopyranosyl-8- O-P-acetyl-1aH,5aH,6PH,7aH-guai-3 (4),10 (14), 11 (13)-triene-15-methyl-6,12-olide, and 3- O-P-glucopyranosyl-8- O-P- (4-hydroxyphenyl)-lactyl-1aH,5aH,6PH,7aH-guai-3 (4),10 (14),11 (13)-triene-15-methyl-6,12-olide. Their structures were established by spectroscopic methods.