T2 carcinoma of the tongue: the histopathologist’s perspective

The histological characteristics and extent of tumour spread at the primary site and in the neck are described in a series of 50 patients with a T2 squamous cell carcinoma of the oral tongue. The likely site of origin was lateral tongue in 29 cases and ventral tongue in 21 cases. Simultaneous tumour...

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Bibliographic Details
Published in:British journal of oral & maxillofacial surgery 1999-06, Vol.37 (3), p.187-193
Main Author: Woolgar, J.A.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Dentistry
Female
Humans
Lymphatic Metastasis
Male
Medical sciences
Middle Aged
Neck
Neoplasm Staging
Otorhinolaryngology. Stomatology
Prognosis
Radiotherapy, Adjuvant
Tongue - pathology
Tongue Neoplasms - pathology
Tongue Neoplasms - radiotherapy
Tongue Neoplasms - surgery
Treatment Outcome
Tumors
Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
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Summary:The histological characteristics and extent of tumour spread at the primary site and in the neck are described in a series of 50 patients with a T2 squamous cell carcinoma of the oral tongue. The likely site of origin was lateral tongue in 29 cases and ventral tongue in 21 cases. Simultaneous tumours were evident in four resections and multifocal dysplasia in a further 13. Lymph node metastasis was diagnosed histologically in 27 cases, including one case with bilateral metastases. Comparison of the groups, with and without metastasis, showed significant differences in tumour thickness, tumour diameter, multifactorial histological malignancy grade, vessel invasion and nerve invasion. The number of positive lymph nodes per patient ranged from 1 to 16 (mean 3), and 17 dissections showed spread beyond the nodal capsule. Postoperative follow-up ranged from 1 to 6 years and, at the time of analysis, 18 patients had died of or with disease. Loco-regional failure was related to ‘high-risk’ features at the primary site and extracapsular spread in the neck.
ISSN:0266-4356
1532-1940
DOI:10.1054/bjom.1999.0034