Efficacy of cyclosporine plus etretinate in the treatment of erythrodermic psoriasis (three case reports)

Background Association of different treatments are often used in erythrodermic psoriasis in order to increase the effectiveness and decrease the incidence of side effects due to single drugs. Materials and methods Three in-patients affected by erythrodermic psoriasis, not responding to cyclosporine,...

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Bibliographic Details
Published in:Journal of the European Academy of Dermatology and Venereology 1998-09, Vol.11 (2), p.177-179
Main Authors: Kokelj, Franco, Plozzer, Carmela, Torsello, Pierpaolo, Trevisan, Giusto
Format: Article
Language:English
Subjects:
Aged
Cyclosporine
Cyclosporine - therapeutic use
Dermatologic Agents
Erythrodermic psoriasis
Etretinate
Etretinate - therapeutic use
Humans
Male
Middle Aged
Psoriasis
Psoriasis - drug therapy
Skin - drug effects
Skin - pathology
Treatment Outcome
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Summary:Background Association of different treatments are often used in erythrodermic psoriasis in order to increase the effectiveness and decrease the incidence of side effects due to single drugs. Materials and methods Three in-patients affected by erythrodermic psoriasis, not responding to cyclosporine, (two patients) and etretinate, (one patient), were treated with the association cyclosporine plus etretinate. Results Clinical response was prompt to the combined therapy. The two drugs were tapering off gradually over 6 months; the patients maintained the remission for prolonged period. Conclusions Combined cyclosporine-etretinate therapy may be considered as an effective and well tolerated treatment of erythrodermic psoriasis in patients not responding to monotherapy regimen.
ISSN:0926-9959
1468-3083
DOI:10.1016/S0926-9959(98)00060-9