Management of labor in Eisenmenger syndrome with inhaled nitric oxide

Administration of nitric oxide by means of inhalation during the labor of a woman with Eisenmenger’s syndrome caused by an atrial septal defect resulted in improved oxygenation and initial pulmonary arterial pressure. She gave birth to a live infant at 34 weeks’ gestation but died of worsening pulmo...

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Bibliographic Details
Published in:American journal of obstetrics and gynecology 1999-08, Vol.181 (2), p.419-423
Main Authors: Lust, Karin M., Boots, Robert J., Dooris, Mark, Wilson, John
Format: Article
Language:English
Subjects:
Administration, Inhalation
Adult
Bed Rest
Biological and medical sciences
Cardiovascular system
Eisenmenger Complex - complications
Eisenmenger Complex - therapy
Eisenmenger’s syndrome
Female
Gestational Age
Heparin - therapeutic use
Humans
labor
Labor, Obstetric
Medical sciences
Miscellaneous
nitric oxide
Nitric Oxide - administration & dosage
Nitric Oxide - therapeutic use
Oxygen - administration & dosage
Oxytocin - therapeutic use
Pharmacology. Drug treatments
Postpartum Hemorrhage - drug therapy
Pregnancy
Pregnancy Complications, Cardiovascular - therapy
pulmonary hypertension
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Description
Summary:Administration of nitric oxide by means of inhalation during the labor of a woman with Eisenmenger’s syndrome caused by an atrial septal defect resulted in improved oxygenation and initial pulmonary arterial pressure. She gave birth to a live infant at 34 weeks’ gestation but died of worsening pulmonary hypertension and heart failure 21 days post partum. (Am J Obstet Gynecol 1999;181:419-23.)
ISSN:0002-9378
1097-6868
DOI:10.1016/S0002-9378(99)70572-7