Cytostatic activity of some compounds from the unsaponifiable fraction obtained from virgin olive oil

Oleuropein, tyrosol, squalene and the fraction of sterols and triterpenoid diacohols from the unsaponifiable fraction obtained from virgin olive oil have been tested for its possible cytostatic activity McCoy cells, using 6-mercaptoropurine as a positive control. The samples of sterols and triterpen...

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Bibliographic Details
Published in:Farmaco (Società chimica italiana : 1989) 1998-06, Vol.53 (6), p.448-449
Main Authors: Saenz, M.T., Garcia, M.D., Ahumada, M.C., Ruiz, V.
Format: Article
Language:English
Subjects:
Antineoplastic Agents, Phytogenic - isolation & purification
Antineoplastic Agents, Phytogenic - pharmacology
Biological and medical sciences
Cell Division - drug effects
Cell Line
Cytostatic activity
General pharmacology
Humans
Iridoids
Medical sciences
Oleuropein
Olive Oil
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Phenylethyl Alcohol - analogs & derivatives
Phenylethyl Alcohol - pharmacology
Plant Oils - chemistry
Pyrans - pharmacology
Squalene - pharmacology
Sterols
Sterols - pharmacology
Triterpenes - pharmacology
Tyrosol
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Summary:Oleuropein, tyrosol, squalene and the fraction of sterols and triterpenoid diacohols from the unsaponifiable fraction obtained from virgin olive oil have been tested for its possible cytostatic activity McCoy cells, using 6-mercaptoropurine as a positive control. The samples of sterols and triterpenic dialcohols showed a strong activity.
ISSN:0014-827X
1879-0569
DOI:10.1016/S0014-827X(98)00043-3