Magnetic resonance T2 measurements of the normal human lung in vivo with ultra-short echo times

The objective of this study was to measure T2* values of the normal human lung in vivo during breathhold using a rapid gradient-echo sequence with ultra-short echo times (TE). A sagittal slice of the right lung was imaged in six volunteers with various TE ranging from 0.5 ms to 5 ms using a clinical...

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Bibliographic Details
Published in:Magnetic resonance imaging 1999-09, Vol.17 (7), p.997-1000
Main Authors: STOCK, K. W, QUN CHEN, HATABU, H, EDELMAN, R. R
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Female
Humans
Investigative techniques, diagnostic techniques (general aspects)
Lung - anatomy & histology
Magnetic Resonance Imaging - methods
Male
Medical sciences
Middle Aged
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Reference Values
Respiratory system
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Summary:The objective of this study was to measure T2* values of the normal human lung in vivo during breathhold using a rapid gradient-echo sequence with ultra-short echo times (TE). A sagittal slice of the right lung was imaged in six volunteers with various TE ranging from 0.5 ms to 5 ms using a clinical 1.5 Tesla MR scanner. T2* values were calculated in a region of interest in the dependent and non-dependent lung. In the dependent lung, T2* values of 1.1 ms+/-0.15 ms were measured, and in the non-dependent lung, 0.86 ms+/-0.11 (p < 0.01). T2* measurements of the normal human lung during breathhold are feasible with a clinical MR unit. The short T2* values require the use of very short TE times (< 2.5 ms) in gradient-echo sequences to obtain adequate signal intensity from lung tissue.
ISSN:0730-725X
1873-5894
DOI:10.1016/s0730-725x(99)00047-8