Rheologic properties of mammalian erythrocytes: relationship to transport ATPases

• Published in: Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 1998-07, Vol.120 (3), p.493-498
• Main Authors: Katyukhin, L.N, Kazennov, A.M, Maslova, M.N, Matskevich, Yu.A
• Format: Article
• Language: English
• Subjects: Adult; Animals; Ca 2+-ATPase; Calcium-Transporting ATPases - blood; Cricetinae; Dogs; Ektacytometry; Erythrocyte Count; Erythrocyte deformability; Erythrocyte Deformability - physiology; Erythrocyte Indices; Erythrocytes - enzymology; Guinea Pigs; Hematocrit; Hemoglobins - analysis; Hemorheology; Humans; In Vitro Techniques; Kinetics; Male; Mesocricetus; Mice; Mice, Inbred CBA; Na +, K +-ATPase; Nonnucleated red blood cells; Rabbits; Rats; Rats, Wistar; Red cell indices; Red cell rheology; Sodium-Potassium-Exchanging ATPase - blood; Species Specificity
• ISSN: 1096-4959; 1879-1107
• DOI: 10.1016/S0305-0491(98)10035-4

Rheologic properties of erythrocytes and activities of their Ca 2+-ATPase and Na +, K +-ATPase were analyzed together with standard erythrocyte values in seven mammalian species (man, rat, mouse, rabbit, hamster, guinea pig and dog). The number of erythrocytes in the blood of animals investigated correlated inversely with the mean cell volume (MCV) ( r=−0.936, P=0.002) and the mean cell hemoglobin content (MCH) ( r=−0.923, P=0.003). MCV and MCH also showed a high direct correlation with each other ( r=0.907, P=0.005). The maximal erythrocyte deformability (DI max) measured with ektacytometry was inversely proportional to the MCV and MCH ( r=−0.854, P=0.014, and r=−0.940, P