Myoepithelioma of soft tissue

A myoepithelioma occurred in the subcutaneous tissue of the right shoulder of a 28‐year‐old man. The well‐demarcated nodular tumor (3.0 × 2.8 cm) was located in the subcutaneous tissue with no adhesion to the deltoid muscle. The tumor was composed of a fascicular proliferation of spindle cells with...

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Bibliographic Details
Published in:Pathology international 1999-06, Vol.49 (6), p.571-576
Main Authors: Sasaguri, Takakazu, Tanimoto, Akihide, Arima, Nobuyuki, Hamada, Tetsuo, Hashimoto, Hiroshi, Sasaguri, Yasuyuki
Format: Article
Language:English
Subjects:
Adult
Antibodies, Monoclonal
Biomarkers, Tumor - analysis
Diagnosis, Differential
electron microscopy
Epithelioid Cells - ultrastructure
Humans
Immunoenzyme Techniques
immunohistochemistry
Leiomyosarcoma - diagnosis
Male
myoepithelioma
Myoepithelioma - chemistry
Myoepithelioma - pathology
Myoepithelioma - surgery
Shoulder - pathology
soft tissue
Soft Tissue Neoplasms - chemistry
Soft Tissue Neoplasms - pathology
Soft Tissue Neoplasms - surgery
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Summary:A myoepithelioma occurred in the subcutaneous tissue of the right shoulder of a 28‐year‐old man. The well‐demarcated nodular tumor (3.0 × 2.8 cm) was located in the subcutaneous tissue with no adhesion to the deltoid muscle. The tumor was composed of a fascicular proliferation of spindle cells with variable amounts of stroma and showed areas of sheets of epithelioid cells. In most areas, the tumor cells had uniform nuclei, but pleomorphic epithelioid cells were focally present. Mitotic activity was three per 10 high‐power fields. No ductular structure was found throughout the tumor. Immunohistochemical and ultrastructural studies confirmed the myoepithelial origin of the tumor cells. The occurrence of myoepithelioma in the subcutaneous tissue has been rarely reported. Even though the tumor showed no aggressive behavior on the 2‐year follow‐up, it is still too early to comment definitely on the behav‐ ior of myoepithelioma of the subcutaneous tissue. This case provides further information about soft tissue myoepithelioma.
ISSN:1320-5463
1440-1827
DOI:10.1046/j.1440-1827.1999.00912.x