Power Doppler in breast tumours: a comparison with conventional colour doppler imaging

• Published in: European journal of ultrasound 1998-08, Vol.7 (3), p.175-181
• Main Authors: Wright, I.A, Pugh, N.D, Lyons, K, Webster, D.J.T, Mansel, R.E
• Format: Article
• Language: English
• Subjects: Adult; Biological and medical sciences; Breast Diseases - diagnostic imaging; Breast Neoplasms - blood supply; Breast Neoplasms - diagnostic imaging; Breast tumour; Colour Doppler; Diagnosis, Differential; Doppler reference frequency; Female; Genital system. Mammary gland; Humans; Investigative techniques, diagnostic techniques (general aspects); Medical sciences; Middle Aged; Power Doppler; Sensitivity and Specificity; Ultrasonic investigative techniques; Ultrasonography, Doppler, Color - methods; Ultrasonography, Mammary - methods; Vascularity
• ISSN: 0929-8266
• DOI: 10.1016/S0929-8266(98)00040-8

Objective: Tumour vascularity can be assessed in-vivo using Doppler ultrasound. The purpose of this study was to determine whether Power Doppler imaging (PDI) better differentiates benign from malignant breast masses than conventional Colour Doppler imaging (CDI) on the basis of assessment of tumour vascularity. Methods: One-hundred women with solid breast lumps (51 malignant lesions, 49 benign lesions) were investigated using a Toshiba SSA-270A ultrasound machine with a 5.0 MHz (3.75 MHz Doppler reference frequency) or a 7.5 MHz (5.0 MHz Doppler reference frequency) linear array probe. The vascularity within or at the periphery of the mass was subjectively assessed from the CDI and Power Doppler images by two independent observers. It was assumed that the absence of vascularity indicated benignity and the presence of flow malignancy. Results: CDI showed sensitivities of 62 and 42% and specificities of 62 and 62% using the 5 and 7.5 MHz probes respectively. PDI showed sensitivities of 76 and 51% and specificities of 56 and 48% using the 5 and 7.5 MHz probes respectively. A comparison of images of the 59 lesions investigated with both probes on both CDI and PDI concluded that the 5 MHz (3.75 MHz DRF) probe displayed equal vascularity to the 7.5 MHz (5.0 MHz DRF) probe in 76% of cases and greater vascularity in 24% of cases on CDI, and 68 and 31% of cases respectively on PDI. Conclusion: Power Doppler imaging with a 5 MHz (3.75 MHz DRF) probe increases the sensitivity of Doppler ultrasound to malignant breast tumours but the sensitivity achieved is not high enough to propose it as a screening investigation.