Pleural carcinosis confirmed by adjuvant cytological methods: A case report

We describe a case of a 43‐yr‐old woman presenting a progressive pleural effusion. The patient was known to have an acute myeloid leukemia in complete remission after allogenic bone marrow transplantation. Suspicion of pleural carcinosis was raised cytologically and confirmed by immunocytochemistry,...

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Bibliographic Details
Published in:Diagnostic cytopathology 1998-11, Vol.19 (5), p.370-374
Main Authors: Motherby, Helma, Roß, Bernd, Kube, Mary, Germing, Ulrich, Heyll, Axel, Aul, Carlo, Braunstein, Stefan, Gabbert, Helmut Erich, Böcking, Alfred
Format: Article
Language:English
Subjects:
Acute Disease
acute myeloid leukemia
Adenocarcinoma - diagnosis
Adenocarcinoma - genetics
Adenocarcinoma - metabolism
Adult
atomic force microscopy
Biological and medical sciences
Biomarkers, Tumor - analysis
DNA, Neoplasm - analysis
DNA-cytometry
effusion cytology
Fatal Outcome
Female
Humans
Image Cytometry - methods
immunocytochemistry
Immunohistochemistry
Leukemia, Myeloid - complications
Medical sciences
Microscopy, Atomic Force - methods
Pleural Effusion, Malignant - pathology
Pleural Neoplasms - diagnosis
Pleural Neoplasms - genetics
Pleural Neoplasms - metabolism
Pneumology
Tumors of the respiratory system and mediastinum
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Summary:We describe a case of a 43‐yr‐old woman presenting a progressive pleural effusion. The patient was known to have an acute myeloid leukemia in complete remission after allogenic bone marrow transplantation. Suspicion of pleural carcinosis was raised cytologically and confirmed by immunocytochemistry, DNA‐cytometry, and atomic force microscopy. We emphasize the use of these additional methods for the distinction of adenocarcinoma cells in effusions from reactive mesothelial cells. Diagn. Cytopathol. 1998;19:370–374. © 1998 Wiley‐Liss, Inc.
ISSN:8755-1039
1097-0339
DOI:10.1002/(SICI)1097-0339(199811)19:5<370::AID-DC12>3.0.CO;2-5