Importance of levonorgestrel dose in oral contraceptives for effects on coagulation

Combined oral contraceptives show clear differences in effect on the tissue factor-initiated coagulation test of activated protein C resistance, which is dependent on the presence and dosage of levonorgestrel. Multiphasic levonorgestrol oral contraceptives differ from monophasic contraceptives and r...

Full description

Saved in:
Bibliographic Details
Published in:The Lancet (British edition) 1999-09, Vol.354 (9181), p.832-833
Main Authors: Kluft, C, de Maat, MPM, Heinemann, LAJ, Spannagl, M, Schramm, W
Format: Article
Language:English
Subjects:
Activated Protein C Resistance
Biological and medical sciences
Birth control
Blood Coagulation - drug effects
Coagulation
Contraceptives
Contraceptives, Oral, Combined - pharmacology
Contraceptives, Oral, Synthetic - pharmacology
Drug therapy
Drug toxicity and drugs side effects treatment
Female
Humans
Levonorgestrel - administration & dosage
Levonorgestrel - pharmacology
Medical sciences
Pharmacology. Drug treatments
Population
Proteins
Side effects
Toxicity: blood
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Combined oral contraceptives show clear differences in effect on the tissue factor-initiated coagulation test of activated protein C resistance, which is dependent on the presence and dosage of levonorgestrel. Multiphasic levonorgestrol oral contraceptives differ from monophasic contraceptives and resemble third-generation contraceptives.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(99)80017-8