Cerebrovascular disease and threshold for dementia in the early stages of Alzheimer's disease

Cerebrovascular disease and Alzheimer's disease commonly occur together in the elderly and each may contribute to dementia. Here we present evidence that Cerebrovascular disease significantly worsens cognitive performance in the earliest stages of Alzheimer's disease.

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Bibliographic Details
Published in:The Lancet (British edition) 1999-09, Vol.354 (9182), p.919-920
Main Authors: Esiri, Margaret M, Nagy, Zsuzsanna, Smith, Maria Z, Barnetson, Lin, Smith, A David
Format: Article
Language:English
Subjects:
Aged
Alzheimer Disease - diagnosis
Alzheimer Disease - pathology
Alzheimer's disease
Biological and medical sciences
Brain - pathology
Brain Mapping
Cerebrovascular Disorders - diagnosis
Cerebrovascular Disorders - pathology
Cognitive ability
Cohort Studies
Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
Dementia
Dementia disorders
Dementia, Vascular - diagnosis
Dementia, Vascular - pathology
Female
Geriatrics
Humans
Longitudinal Studies
Male
Medical disorders
Medical research
Medical sciences
Neurology
Neuropsychological Tests
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Risk Factors
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Description
Summary:Cerebrovascular disease and Alzheimer's disease commonly occur together in the elderly and each may contribute to dementia. Here we present evidence that Cerebrovascular disease significantly worsens cognitive performance in the earliest stages of Alzheimer's disease.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(99)02355-7