The protective immune response of yellowtail Seriola quinqueradiata to the bacterial fish pathogen Lactococcus garvieae

Yellowtail Seriola quinqueradiata were immunized with 2 different Lactococcus garvieae bacterin, formalin-killed KG- phenotype cells (capsulated phenotype) and formalin-killed KG+ phenotype cells (unencapsulated phenotype). These 2 injected vaccines conferred long-term protection to yellowtail again...

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Bibliographic Details
Published in:Diseases of aquatic organisms 1999-07, Vol.37 (2), p.121-126
Main Authors: OOYAMA, T, KERA, A, OKADA, T, INGLIS, V, YOSHIDA, T
Format: Article
Language:English
Subjects:
Agglutination Tests - veterinary
Animal aquaculture
Animal productions
Animals
Antibodies, Bacterial - blood
Bacterial Capsules - immunology
Bacterial Vaccines
Bacteriology
Biological and medical sciences
Fish Diseases - immunology
Fish Diseases - microbiology
Fish Diseases - prevention & control
Fishes
Fundamental and applied biological sciences. Psychology
Gram-Positive Bacterial Infections - immunology
Gram-Positive Bacterial Infections - prevention & control
Gram-Positive Bacterial Infections - veterinary
Immunization, Passive
Lactococcus - classification
Lactococcus - immunology
Lactococcus garvieae
Microbiology
Phagocytosis
Phenotype
Pisciculture
Seriola quinqueradiata
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies
Vertebrate aquaculture
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Summary:Yellowtail Seriola quinqueradiata were immunized with 2 different Lactococcus garvieae bacterin, formalin-killed KG- phenotype cells (capsulated phenotype) and formalin-killed KG+ phenotype cells (unencapsulated phenotype). These 2 injected vaccines conferred long-term protection to yellowtail against an artificial infection of an encapsulated Lactococcus garvieae strain with long-lasting agglutinating titres against KG+ phenotype cells. However, no agglutinating titres or low agglutinating titres against KG- phenotype cells were detected in fish given each of these bacterin. These results suggested that a capsule in KG- phenotype cells apparently affects their immunogenicity, but the antigens which conferred protection to fish against lactococcal infection may be located on the surface of KG+ phenotype cells, and are not cell capsules in KG- phenotype cells. The protection offered by a formalin-killed KG+ phenotype cell vaccine would not appear to be strain specific. Encapsulated L. garvieae cells were well phagocytosed, and fimbrie-like appendages were seen in KG- phenotype cells after treatment with yellowtail immune serum.
ISSN:0177-5103
1616-1580
DOI:10.3354/dao037121