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Systolic ejection murmurs in the era of modern cardiology : What do we really know?

The basics of pulsatile ejection dynamics are reviewed in order to clarify the relationships among left ventricular and aortic pressures, intra-left ventricular and aortic flow velocities, and cardiovascular sound. The principles of turbulent flow are examined using the Reynolds number concept, and...

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Published in:	Journal of the American College of Cardiology 1998-11, Vol.32 (6), p.1596-1602
Main Author:	MURGO, J. P
Format:	Article
Language:	English
Subjects:	Aortic Valve Stenosis - physiopathology Biological and medical sciences Blood Pressure - physiology Cardiology - trends Cardiology. Vascular system Cardiomyopathy, Hypertrophic - complications Cardiomyopathy, Hypertrophic - physiopathology Cardiopathies: etiologic forms (general aspects and miscellaneous) Coronary Circulation - physiology Heart Heart Murmurs - etiology Humans Medical sciences Reference Values Systole Ventricular Function, Left
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container_title	Journal of the American College of Cardiology
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description	The basics of pulsatile ejection dynamics are reviewed in order to clarify the relationships among left ventricular and aortic pressures, intra-left ventricular and aortic flow velocities, and cardiovascular sound. The principles of turbulent flow are examined using the Reynolds number concept, and the evidence for cause-and-effect relationships between turbulent flow and murmur generation is presented. Examples of hemodynamics and phonocardiography are given for normal subjects and are compared to patients with aortic stenosis and hypertrophic cardiomyopathy. The concepts presented are used to analyze the results of a new study suggesting increased intraventricular velocities as a new cause for systolic murmurs in adults.
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subjects	Aortic Valve Stenosis - physiopathology Biological and medical sciences Blood Pressure - physiology Cardiology - trends Cardiology. Vascular system Cardiomyopathy, Hypertrophic - complications Cardiomyopathy, Hypertrophic - physiopathology Cardiopathies: etiologic forms (general aspects and miscellaneous) Coronary Circulation - physiology Heart Heart Murmurs - etiology Humans Medical sciences Reference Values Systole Ventricular Function, Left
title	Systolic ejection murmurs in the era of modern cardiology : What do we really know?
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