Granulocytic sarcoma presenting as cauda equina syndrome

Granulocytic sarcoma (GS) is a tumour formed by myeloid precursors in an extramedullary site and is associated with myeloid leukaemias and other myeloproliferative disorders. We present a patient with symptoms of cauda equina compression where MRI of the spine showed extradural lesions at S1 and L3...

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Bibliographic Details
Published in:Clinical neurology and neurosurgery 1998-09, Vol.100 (3), p.205-208
Main Authors: Sandhu, G.S, Ghufoor, K, Gonzalez-Garcia, J, Elexpuru-Camiruaga, J.A
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Biopsy, Needle
Bone Marrow - pathology
Cauda Equina
Chloroma
Diagnosis, Differential
Fatal Outcome
Granulocytic sarcoma
Hematologic and hematopoietic diseases
Humans
Leukemia, Monocytic, Acute - diagnosis
Leukemia, Monocytic, Acute - therapy
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Magnetic Resonance Imaging
Male
Medical sciences
Nerve Compression Syndromes - diagnosis
Reoperation
Spinal cord compression
Tomography, X-Ray Computed
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Summary:Granulocytic sarcoma (GS) is a tumour formed by myeloid precursors in an extramedullary site and is associated with myeloid leukaemias and other myeloproliferative disorders. We present a patient with symptoms of cauda equina compression where MRI of the spine showed extradural lesions at S1 and L3 levels. This patient had normal bone marrow and peripheral blood for a further 6 weeks from onset of symptoms. Such aleukaemic presentations of GS are rare and have potential for misdiagnosis and delay in treatment. Therefore we recommend early open biopsy of such tumours.
ISSN:0303-8467
1872-6968
DOI:10.1016/S0303-8467(98)00021-3