Synthesis of oligosaccharides containing β- d-Gal-(1→3)-O-(6-O-sulfo- β- d-GlcNAc) as a terminal unit

The chemical synthesis of β- d-Gal-(1→3)-6-O-SO 3Na- β- d-GlcNAc-(1→6)- α- d-Man-O-C 6H 4NO 2 ( 1) and β- d-Gal-(1→3)-6-O-SO 3Na- β- d-GlcNAc-(1→2)- α- d-Man-OMe ( 2) is reported using a key glycosyl donor, phenyl O-(2,3,4,6-tetra- O-acetyl- β- d-galactopyranosyl)-(1→3)-4,6-di- O-chloroacetyl-2-deox...

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Bibliographic Details
Published in:Carbohydrate research 1998-09, Vol.311 (3), p.165-169
Main Authors: Huang, Bao-Guo, Jain, Rakesh K., Tabaczynski, Walter A., Alderfer, James L., Matta, Khushi L.
Format: Article
Language:English
Subjects:
Carbohydrate Sequence
Glycosylation
Magnetic Resonance Spectroscopy
Molecular Sequence Data
Oligosaccharides - chemical synthesis
Spectrometry, Mass, Fast Atom Bombardment
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Summary:The chemical synthesis of β- d-Gal-(1→3)-6-O-SO 3Na- β- d-GlcNAc-(1→6)- α- d-Man-O-C 6H 4NO 2 ( 1) and β- d-Gal-(1→3)-6-O-SO 3Na- β- d-GlcNAc-(1→2)- α- d-Man-OMe ( 2) is reported using a key glycosyl donor, phenyl O-(2,3,4,6-tetra- O-acetyl- β- d-galactopyranosyl)-(1→3)-4,6-di- O-chloroacetyl-2-deoxy-2-phthalimido-1-thio- β- d-glucopyranoside ( 3).
ISSN:0008-6215
1873-426X
DOI:10.1016/S0008-6215(98)00166-9