L-proline as a nitrogen source increases the susceptibility of Saccharomyces cerevisiae S288c to fluconazole

Fluconazole inhibition of Saccharomyces cerevisiae S288c growth was evaluated in media containing ammonia, L-proline or L-leucine as a nitrogen source. Growth inhibition by fluconazole was maximum when L-proline was used as a nitrogen source, while rhodamine 6G accumulation and fluconazole resistanc...

Full description

Saved in:
Bibliographic Details
Published in:Folia microbiologica 1998, Vol.43 (4), p.403-405
Main Authors: STELLA, C, COSTANZO, R, BURGOS, H. I, SAENZ, D, VENERUS, R. D
Format: Article
Language:English
Subjects:
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antifungal agents
Antifungal Agents - pharmacology
Biological and medical sciences
Culture Media
Drug Resistance, Microbial
Fluconazole - pharmacology
Medical sciences
Microbial Sensitivity Tests
Nitrogen - metabolism
Pharmacology. Drug treatments
Proline - metabolism
Rhodamines - metabolism
Saccharomyces cerevisiae
Saccharomyces cerevisiae - drug effects
Saccharomyces cerevisiae - growth & development
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Fluconazole inhibition of Saccharomyces cerevisiae S288c growth was evaluated in media containing ammonia, L-proline or L-leucine as a nitrogen source. Growth inhibition by fluconazole was maximum when L-proline was used as a nitrogen source, while rhodamine 6G accumulation and fluconazole resistance were the highest when ammonia was the sole nitrogen source.
ISSN:0015-5632
1874-9356
DOI:10.1007/BF02818581