MRI of focal cortical dysplasia

We studied nine cases of focal cortical dysplasia (FCD) by MRI, with surface-rendered 3D reconstructions. One case was also examined using single-voxel proton MR spectroscopy (MRS). The histological features were reviewed and correlated with the MRI findings. The gyri affected by FCD were enlarged a...

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Bibliographic Details
Published in:Neuroradiology 1998-10, Vol.40 (10), p.675-683
Main Authors: LEE, B. C. P, SCHMIDT, R. E, HATFIELD, G. A, BOURGEOIS, B, PARK, T. S
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cerebral Cortex - chemistry
Cerebral Cortex - pathology
Child
Child, Preschool
Epilepsy - metabolism
Epilepsy - pathology
Humans
Image Processing, Computer-Assisted
Infant
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy
Malformations of the nervous system
Medical sciences
Neurology
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Summary:We studied nine cases of focal cortical dysplasia (FCD) by MRI, with surface-rendered 3D reconstructions. One case was also examined using single-voxel proton MR spectroscopy (MRS). The histological features were reviewed and correlated with the MRI findings. The gyri affected by FCD were enlarged and the signal of the cortex was slightly increased on T1-weighted images. The gray-white junction was indistinct. Signal from the subcortical white matter was decreased on T1- and increased on T2-weighted images in most cases. Contrast enhancement was seen in two cases. Proton MRS showed a spectrum identical to that of normal brain.
ISSN:0028-3940
1432-1920
DOI:10.1007/s002340050664