Novel CDC25A Phosphatase Inhibitors from Pyrolysis of 3-α-Azido-B-homo-6-oxa-4-cholesten-7-one on Silica Gel

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Bibliographic Details
Published in:Journal of medicinal chemistry 1998-11, Vol.41 (24), p.4677-4680
Main Authors: Peng, Hairuo, Zalkow, Leon H, Abraham, Robert T, Powis, Garth
Format: Article
Language:English
Subjects:
Acetates - chemical synthesis
Acetates - chemistry
Acetates - pharmacology
Antineoplastic agents
Azides - chemistry
Biological and medical sciences
cdc25 Phosphatases
Cholestenones - chemistry
Crystallography, X-Ray
Enzyme Inhibitors - chemical synthesis
Enzyme Inhibitors - chemistry
Enzyme Inhibitors - pharmacology
Fluoresceins - metabolism
Gels
General aspects
Indans - chemical synthesis
Indans - chemistry
Indans - pharmacology
Medical sciences
Molecular Conformation
Pharmacology. Drug treatments
Phosphorylation
Protein Tyrosine Phosphatases - antagonists & inhibitors
Silica Gel
Silicon Dioxide
Structure-Activity Relationship
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ISSN:0022-2623
1520-4804
DOI:10.1021/jm980500r