The Efficacy of Topical Ciprofloxacin in the Treatment of Chronic Suppurative Otitis Media

We conducted a test of the efficacy of ciprofloxacin eardrops in 80 patients (95 ears) with otorrhea due to chronic suppurative otitis media in two treatment settings. One group (n=40; 47 ears) received daily ciprofloxacin therapy plus aspiration in the clinic. The other group (n=40; 48 ears) self-a...

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Bibliographic Details
Published in:Ear, nose, & throat journal nose, & throat journal, 1998-11, Vol.77 (11), p.904-909
Main Authors: Kiris, Muzaffer, Berktas, Mustafa, Egeli, Erol, Kutluhan, Ahmet
Format: Article
Language:English
Subjects:
Administration, Topical
Adolescent
Adult
Aged
Anti-Infective Agents - administration & dosage
Bacteria - isolation & purification
Biological and medical sciences
Child
Child, Preschool
Chronic Disease
Ciprofloxacin - administration & dosage
Ent. Stomatology
Female
Follow-Up Studies
Humans
Infant
Male
Medical sciences
Microbial Sensitivity Tests
Middle Aged
Otitis Media, Suppurative - drug therapy
Otitis Media, Suppurative - microbiology
Pharmacology. Drug treatments
Treatment Outcome
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Summary:We conducted a test of the efficacy of ciprofloxacin eardrops in 80 patients (95 ears) with otorrhea due to chronic suppurative otitis media in two treatment settings. One group (n=40; 47 ears) received daily ciprofloxacin therapy plus aspiration in the clinic. The other group (n=40; 48 ears) self-administered ciprofloxacin at home. Overall, otorrhea resolved in 88% of all ears within 12 days of the initiation of treatment. The clinic-treated patients tended to respond more rapidly than did the self-treated patients, but there was no statistically significant difference in success rates between the two groups. Side effects were negligible. We conclude that empiric topical ciprofloxacin therapy is an effective, safe and relatively inexpensive treatment for otorrhea in patients with chronic otitis media.
ISSN:0145-5613
1942-7522
DOI:10.1177/014556139807701108