Zinc deficiency manifested by dermatitis and visual dysfunction in a patient with Crohn's disease

We report a case of Crohn's disease with low serum zinc concentration in a 26-year-old woman. She demonstrated acrodermatitis enteropathica and decreased visual acuity during total parenteral nutrition. Subsequent intravenous zinc supplementation resulted in alleviation of the skin lesions and...

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Bibliographic Details
Published in:Journal of gastroenterology 1998-12, Vol.33 (6), p.876-879
Main Authors: Myung, S J, Yang, S K, Jung, H Y, Jung, S A, Kang, G H, Ha, H K, Hong, W S, Min, Y I
Format: Article
Language:English
Subjects:
Acrodermatitis - diagnosis
Acrodermatitis - etiology
Adult
Crohn Disease - complications
Crohn Disease - drug therapy
Diagnosis, Differential
Facial Dermatoses - diagnosis
Facial Dermatoses - etiology
Female
Follow-Up Studies
Humans
Treatment Outcome
Vision Disorders - diagnosis
Vision Disorders - etiology
Zinc - deficiency
Zinc - metabolism
Zinc - therapeutic use
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Description
Summary:We report a case of Crohn's disease with low serum zinc concentration in a 26-year-old woman. She demonstrated acrodermatitis enteropathica and decreased visual acuity during total parenteral nutrition. Subsequent intravenous zinc supplementation resulted in alleviation of the skin lesions and improvement of visual acuity. This case supports the notion that depressed serum zinc in Crohn's disease may cause clinical manifestations, such as acrodermatitis enteropathica and retinal dysfunction, which may be correctable with zinc supplementation.
ISSN:0944-1174
1435-5922
DOI:10.1007/s005350050192