Worm thermotaxis: a model system for analyzing thermosensation and neural plasticity

Elucidation of the principal mechanism for sensory transduction, learning and memory is a fundamental question in neurobiology. The simple nervous system composed of only 302 neurons and the description of neural wiring combined with developed imaging techniques facilitate cellular and circuit level...

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Bibliographic Details
Published in:Current opinion in neurobiology 2007-12, Vol.17 (6), p.712-719
Main Authors: Mori, Ikue, Sasakura, Hiroyuki, Kuhara, Atsushi
Format: Article
Language:English
Subjects:
Animals
Behavior, Animal - physiology
Caenorhabditis elegans - physiology
Models, Biological
Movement - physiology
Neurology
Neuronal Plasticity - physiology
Psychiatry
Thermosensing - physiology
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Summary:Elucidation of the principal mechanism for sensory transduction, learning and memory is a fundamental question in neurobiology. The simple nervous system composed of only 302 neurons and the description of neural wiring combined with developed imaging techniques facilitate cellular and circuit level analysis of behavior in the nematode Caenorhabditis elegans . Recent comprehensive analysis of worm thermotaxis, an experience-modulated behavior, has begun to reveal molecular, cellular, and neural circuit basis of thermosensation and neural plasticity.
ISSN:0959-4388
1873-6882
DOI:10.1016/j.conb.2007.11.010