Spontaneous closure of muscular ventricular septal defect identified by echocardiography in neonates

Muscular ventricular septal defects were diagnosed by echocardiography in 97 neonates within 7 days of birth. In 82 of the neonates (84.5%), the defect was solitary, while 15 had multiple defects. The solitary defects was located at mid-septal, apical, anterior and inlet locations in 42 (51.2%), 21...

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Bibliographic Details
Published in:Cardiology in the young 1998-10, Vol.8 (4), p.500-505
Main Authors: Du, Zhong-Dong, Roguin, Nathan, Wu, Xing-Jian
Format: Article
Language:English
Subjects:
Echocardiography, Doppler
Female
Heart Septal Defects, Ventricular - diagnostic imaging
Heart Septal Defects, Ventricular - pathology
Humans
Infant, Newborn
Male
Muscular ventricular septal defect
neonate
Original Articles
Sensitivity and Specificity
spontaneous closure
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Summary:Muscular ventricular septal defects were diagnosed by echocardiography in 97 neonates within 7 days of birth. In 82 of the neonates (84.5%), the defect was solitary, while 15 had multiple defects. The solitary defects was located at mid-septal, apical, anterior and inlet locations in 42 (51.2%), 21 (25.6%), 14 (17.1%) and 5 (6.1%) neonates, respectively. Multiple defects occurred in the apical, anterior and mid-septal areas. The diameter of the solitary defects ranged from 1 to 6 mm (2.3 ± 0.8 mm), while the multiple lesions were 1 to 4 mm in diameter (2.1 2.3 ± 0.8 mm 0.8 mm) in 28 instances in which they could measured. It proved possible to follow 79 of the patients for period of 10 to 13 months. The defects closed spontaneously in 56 (84.8%) of 66 patients with a single defect, and in 7 (53.8%) of 13 of those with multiple defects (P
ISSN:1047-9511
1467-1107
DOI:10.1017/S1047951100007174