Atheromatous embolization

Atheromatous embolization is a multisystem disease complicating advanced atherosclerosis. It occurs most often as a complication of angiography, an endovascular procedure or cardiovascular surgery. Atheromatous embolization can present in a subtle manner where it is often under-recognized, or with c...

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Bibliographic Details
Published in:Vascular medicine (London, England) England), 2005-11, Vol.10 (4), p.309-326
Main Authors: Liew, Yin Ping, Bartholomew, John R
Format: Article
Language:English
Subjects:
Adrenal Cortex Hormones - therapeutic use
Angiography
Atherosclerosis - diagnosis
Atherosclerosis - etiology
Atherosclerosis - therapy
Biological and medical sciences
Blood and lymphatic vessels
Cardiac Surgical Procedures
Cardiology. Vascular system
Diagnosis, Differential
Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous
Embolism, Cholesterol - diagnosis
Embolism, Cholesterol - prevention & control
Embolism, Cholesterol - therapy
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use
Kidney Diseases - diagnosis
Kidney Diseases - therapy
Medical sciences
Risk Factors
Skin Diseases, Vascular - diagnosis
Skin Diseases, Vascular - therapy
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Summary:Atheromatous embolization is a multisystem disease complicating advanced atherosclerosis. It occurs most often as a complication of angiography, an endovascular procedure or cardiovascular surgery. Atheromatous embolization can present in a subtle manner where it is often under-recognized, or with catastrophic results including myocardial infarction, strake or acute renal failure. It may mimic other disease processes and often goes underdiagnosed and undertreated. A high clinical suspicion is the key to diagnosis. Atheromatous embolization results in significant morbidity and mortality; therefore, early recognition followed by aggressive management may help to prevent end-organ damage and improve overall clinical outcomes. Management strategies should include risk factor modification, prevention of further insults by discontinuing or avoiding predisposing factors, supportive treatment and interventional or surgical approaches to remove the atheroembolic source. Atheromatous embolization is expected to increase as our population ages and the epidemics of diabetes mellitus and obesity increase.
ISSN:1358-836X
1358-863X
1477-0377
DOI:10.1191/1358863x05vm640ra