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Phaeohyphomycosis: an unusual pituitary mass

A 64-year-old Caucasian woman presented with left eye pain and a transient left oculomotor nerve palsy. Subsequent imaging revealed a mass involving the sphenoid sinus and sella with suprasellar extension. A trans-sphenoidal hypophysectomy was performed. Histopathology showed a fungal infection cons...

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Bibliographic Details
Published in:British journal of neurosurgery 2005-10, Vol.19 (5), p.442-445
Main Authors: Yeung, I. Y. L., Whitelaw, B. C., Hortobágyi, T., Bódi, I., Petrou, M. A., Connor, S. E. J., Thomas, N. W. M.
Format: Article
Language:English
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Summary:A 64-year-old Caucasian woman presented with left eye pain and a transient left oculomotor nerve palsy. Subsequent imaging revealed a mass involving the sphenoid sinus and sella with suprasellar extension. A trans-sphenoidal hypophysectomy was performed. Histopathology showed a fungal infection consistent with phaeohyphomycosis. Development of this lesion is probably attributed to allergic rhinitis and insulin-dependent diabetes mellitus. Intravenous amphotericin and itraconazole treatment resulted in full recovery and the patient remains well at 6-month postoperative follow-up.
ISSN:0268-8697
1360-046X
DOI:10.1080/02688690500390417