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A Case of Extensive Linear Porokeratosis with Evaluation of Topical Tretinoin versus 5‐Flourouracil as Treatment Modalities
A 19‐year‐old male presented with linear raised lesions over extensive areas of his body that followed Blaschko's lines. The lesions were asymptomatic with ridged borders. Histopathology confirmed a diagnosis of porokeratosis. He was given topical tretinoin and topical flourouracil for local ap...
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Published in: | Journal of dermatology 2005-12, Vol.32 (12), p.1000-1004 |
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container_issue | 12 |
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container_title | Journal of dermatology |
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creator | Grover, Chander Goel, Alka Nanda, Soni Khurana, Nita Reddy, Belum Siva Nagi |
description | A 19‐year‐old male presented with linear raised lesions over extensive areas of his body that followed Blaschko's lines. The lesions were asymptomatic with ridged borders. Histopathology confirmed a diagnosis of porokeratosis. He was given topical tretinoin and topical flourouracil for local application on specified areas. The cosmetic acceptability and the safety profile of tretinoin were found to be better than those of flourouracil. However, both the agents were equally efficacious. A rare case of extensive porokeratosis with comparative evaluation of two treatment modalities is hereby presented. |
doi_str_mv | 10.1111/j.1346-8138.2005.tb00890.x |
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source | Wiley-Blackwell Read & Publish Collection |
subjects | Administration, Topical Adult Biopsy, Needle Dose-Response Relationship, Drug Drug Administration Schedule Evaluation Studies as Topic flourouracil Fluorouracil - therapeutic use Follow-Up Studies Humans Immunohistochemistry linear porokeratosis Male Porokeratosis - diagnosis Porokeratosis - drug therapy Porokeratosis - pathology Risk Assessment Severity of Illness Index Treatment Outcome tretinoin Tretinoin - therapeutic use |
title | A Case of Extensive Linear Porokeratosis with Evaluation of Topical Tretinoin versus 5‐Flourouracil as Treatment Modalities |
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