Percutaneous balloon commissurotomy reduces incidence of ischemic cerebral stroke in patients with symptomatic rheumatic mitral stenosis

Abstract Whether percutaneous balloon commissurotomy reduces cerebral stroke in patients with symptomatic rheumatic mitral stenosis remains obscure. This study enrolled 170 such patients undergoing either medical therapy alone ( n = 71) or balloon commissurotomy ( n = 99). In the short term, balloon...

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Bibliographic Details
Published in:International journal of cardiology 2008-01, Vol.123 (2), p.189-190
Main Authors: Liu, Tsun-Jui, Lai, Hui-Chun, Lee, Wen-Lieng, Wang, Kuo-Yang, Wei, Hao-Ji, Ting, Chih-Tai, Lai, Hui-Chin
Format: Article
Language:English
Subjects:
Angioplasty, Balloon
Biological and medical sciences
Brain Ischemia - epidemiology
Brain Ischemia - etiology
Brain Ischemia - prevention & control
Cardiology. Vascular system
Cardiovascular
Commissurotomy
Endocardial and cardiac valvular diseases
Female
Heart
Humans
Incidence
Male
Medical sciences
Middle Aged
Mitral stenosis
Mitral Valve Stenosis - complications
Mitral Valve Stenosis - therapy
Neurology
Rheumatic Heart Disease - complications
Stroke
Stroke - epidemiology
Stroke - etiology
Stroke - prevention & control
Vascular diseases and vascular malformations of the nervous system
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Summary:Abstract Whether percutaneous balloon commissurotomy reduces cerebral stroke in patients with symptomatic rheumatic mitral stenosis remains obscure. This study enrolled 170 such patients undergoing either medical therapy alone ( n = 71) or balloon commissurotomy ( n = 99). In the short term, balloon commissurotomy was successfully accomplished in 99% patients without embolic complications. At follow-up (mean 4.2 ± 3.2 years), patients undergoing commissurotomy encountered significantly rarer ischemic stroke than the medicine group (2% vs. 13%, p = 0.043). Multivariate Cox regression analysis further confirmed balloon commissurotomy as a negative predictor for ischemic stroke (hazard ratio 0.135, p = 0.011). These results lead to the conclusion that percutaneous balloon commissurotomy could substantially decrease the long-term incidence of ischemic cerebral stroke in eligible patients with symptomatic rheumatic mitral stenosis.
ISSN:0167-5273
1874-1754
DOI:10.1016/j.ijcard.2006.11.128