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The prevalence of and risk factors for erosive oesophagitis and non‐erosive reflux disease: a nationwide multicentre prospective study in Korea

Summary Background  Prospective nationwide multicentre studies that have evaluated endoscopic findings and reflux symptoms using a well‐designed questionnaire are very rare. Aim  To compare the prevalence rates of and risk factors for erosive oesophagitis and non‐erosive reflux disease (NERD) in the...

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Published in:Alimentary pharmacology & therapeutics 2008-01, Vol.27 (2), p.173-185
Main Authors: KIM, N., LEE, S. W., CHO, S. I., PARK, C. G., YANG, C. H., KIM, H. S., REW, J. S., MOON, J. S., KIM, S., PARK, S. H., JUNG, H. C., CHUNG, I. S.
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Language:English
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Summary:Summary Background  Prospective nationwide multicentre studies that have evaluated endoscopic findings and reflux symptoms using a well‐designed questionnaire are very rare. Aim  To compare the prevalence rates of and risk factors for erosive oesophagitis and non‐erosive reflux disease (NERD) in the Korean population. Methods  A gastroscopic examination was performed on 25 536 subjects who visited 40 Healthcare Centers for a health check‐up. A gastro‐oesophageal reflux questionnaire and multivariate analysis were used to determine the risk factors for erosive oesophagitis and NERD. Results  2019 (8%) and 996 subjects (4%) had erosive oesophagitis and non‐erosive reflux disease, respectively; only 58% of subjects with erosive oesophagitis had reflux symptoms. Multivariate analysis showed that the risk factors for erosive oesophagitis and NERD differed, i.e. those of erosive oesophagitis were male, a Helicobacter pylori eradication history, alcohol, body mass index ≥25 and hiatal hernia. In contrast, the risk factors for NERD were female, age
ISSN:0269-2813
1365-2036
DOI:10.1111/j.1365-2036.2007.03561.x