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The prevalence of and risk factors for erosive oesophagitis and non‐erosive reflux disease: a nationwide multicentre prospective study in Korea
Summary Background Prospective nationwide multicentre studies that have evaluated endoscopic findings and reflux symptoms using a well‐designed questionnaire are very rare. Aim To compare the prevalence rates of and risk factors for erosive oesophagitis and non‐erosive reflux disease (NERD) in the...
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Published in: | Alimentary pharmacology & therapeutics 2008-01, Vol.27 (2), p.173-185 |
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Main Authors: | , , , , , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Background Prospective nationwide multicentre studies that have evaluated endoscopic findings and reflux symptoms using a well‐designed questionnaire are very rare.
Aim To compare the prevalence rates of and risk factors for erosive oesophagitis and non‐erosive reflux disease (NERD) in the Korean population.
Methods A gastroscopic examination was performed on 25 536 subjects who visited 40 Healthcare Centers for a health check‐up. A gastro‐oesophageal reflux questionnaire and multivariate analysis were used to determine the risk factors for erosive oesophagitis and NERD.
Results 2019 (8%) and 996 subjects (4%) had erosive oesophagitis and non‐erosive reflux disease, respectively; only 58% of subjects with erosive oesophagitis had reflux symptoms. Multivariate analysis showed that the risk factors for erosive oesophagitis and NERD differed, i.e. those of erosive oesophagitis were male, a Helicobacter pylori eradication history, alcohol, body mass index ≥25 and hiatal hernia. In contrast, the risk factors for NERD were female, age |
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ISSN: | 0269-2813 1365-2036 |
DOI: | 10.1111/j.1365-2036.2007.03561.x |