Seasonal effects of Selank on the behavior of hibernating animals

We studied the seasonal effects of peptide preparation Selank on orientation and exploratory activity in 36 arctic ground squirrels Citellus undulatus in the open-field and hole-board tests. Selank most significantly increased behavioral activity of hibernating animals in the spring and fall. The te...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2005-12, Vol.140 (6), p.705-707
Main Authors: Semenova, T P, Kozlovskaya, M M, Zuikov, A V, Kozlovskii, I I, Andreeva, L A
Format: Article
Language:English
Subjects:
Animals
Arctic Regions
Behavior, Animal - drug effects
Citellus undulatus
Female
Hibernation - drug effects
Male
Motor Activity
Movement
Oligopeptides - pharmacology
Peptides - chemistry
Sciuridae
Seasons
Spermophilus
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Summary:We studied the seasonal effects of peptide preparation Selank on orientation and exploratory activity in 36 arctic ground squirrels Citellus undulatus in the open-field and hole-board tests. Selank most significantly increased behavioral activity of hibernating animals in the spring and fall. The test peptide had no effect on locomotor activity of animals. The selective stimulatory effect of Selank on exploratory behavior of hibernating animals was season-dependent. The maximum effect was observed under conditions of seasonal depression-like state.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-006-0060-0