Metachronus malignant rhabdoid tumor of the ileum and adenocarcinoma of lung: a unique case report

Abstract Malignant extrarenal rhabdoid tumors had been described in a variety of anatomic locations including gastrointestinal tract. Carcinomas of small intestine are quite uncommon neoplasms, and those with rhabdoid differentiation are exceedingly rare. These poorly differentiated tumors pose a gr...

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Bibliographic Details
Published in:Annals of diagnostic pathology 2008-02, Vol.12 (1), p.57-61
Main Authors: Sheikh, Salwa Shabbir, MD, FCAP, FASCP, Al-Khatti, Adil A., MD, Amr, Samir S., MD, FCAP
Format: Article
Language:English
Subjects:
Adenocarcinoma
Adenocarcinoma - pathology
Adenocarcinoma - surgery
Anaplastic carcinoma
Disease-Free Survival
Giant cell carcinoma
Humans
Ileal Neoplasms - pathology
Ileal Neoplasms - surgery
Ileum
Lung
Lung Neoplasms - pathology
Lung Neoplasms - surgery
Male
Middle Aged
Neoplasm Staging
Neoplasms, Multiple Primary - pathology
Neoplasms, Multiple Primary - surgery
Pathology
Pleomorphic carcinoma
Rhabdoid tumor
Rhabdoid Tumor - pathology
Rhabdoid Tumor - surgery
Small intestine
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Summary:Abstract Malignant extrarenal rhabdoid tumors had been described in a variety of anatomic locations including gastrointestinal tract. Carcinomas of small intestine are quite uncommon neoplasms, and those with rhabdoid differentiation are exceedingly rare. These poorly differentiated tumors pose a great deal of difficulty in diagnosis as well as in deciding whether they are primary or metastatic in origin because malignant rhabdoid tumors or carcinomas with rhabdoid differentiation of other sites can metastasize to the small intestine. They behave more aggressively than the typical adenocarcinomas of the same location. Herein, we report a 52-year-old patient with primary small bowel malignant rhabdoid tumor, who was completely disease-free after the initial presentation and management. Five years later, he was found to have a lung mass proved to be adenocarcinoma, exhibiting focal giant cell differentiation without rhabdoid features.
ISSN:1092-9134
1532-8198
DOI:10.1016/j.anndiagpath.2006.06.007