SEROLOGIC RESPONSES OF BARBARY SHEEP (AMMOTRAGUS LERVIA), INDIAN ANTELOPE (ANTILOPE CERVICAPRA), WALLAROOS (MACROPUS ROBUSTUS), AND CHIMPANZEES (PAN TROGLODYTES) TO AN INACTIVATED ENCEPHALOMYOCARDITIS VIRUS VACCINE

Encephalomyocarditis virus (EMCV) is a picornavirus with a worldwide distribution, capable of infecting a wide range of species. Episodes of EMCV-associated mortality have been reported in zoos and national parks around the world, including sporadic cases at Taronga Zoo, Sydney. An inactivated EMCV...

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Bibliographic Details
Published in:Journal of zoo and wildlife medicine 2005-03, Vol.36 (1), p.69-73
Main Authors: McLelland, David J, Kirkland, Peter D, Rose, Karrie A, Dixon, Robert J, Smith, Narelle
Format: Article
Language:English
Subjects:
Ammotragus lervia
Animals
Antelopes - immunology
Antibodies, Viral - blood
Antilope cervicapra
Dose-Response Relationship, Immunologic
Encephalomyocarditis virus
Encephalomyocarditis virus - immunology
Female
Macropodidae - immunology
Macropus robustus
Male
Neutralization Tests - veterinary
Pan troglodytes
Pan troglodytes - immunology
Ruminants - immunology
Species Specificity
vaccine
Vaccines, Attenuated
Vaccines, Inactivated
Viral Vaccines - immunology
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Summary:Encephalomyocarditis virus (EMCV) is a picornavirus with a worldwide distribution, capable of infecting a wide range of species. Episodes of EMCV-associated mortality have been reported in zoos and national parks around the world, including sporadic cases at Taronga Zoo, Sydney. An inactivated EMCV vaccine was evaluated by inoculating Barbary sheep (Ammotragus lervia), Indian antelope (Antilope cervicapra), Eastern wallaroos (Macropus robustus), and chimpanzees (Pan troglodytes). A proportion of the vaccinated ungulates were administered a second vaccination 4 wk after the initial dose. Neutralizing antibody titers were monitored for a period of 12 mo. One month after vaccination, all vaccinated groups had developed significant antibody titers that persisted for at least 6 mo. Animals receiving two doses of vaccine had higher titers 3, 6, and 12 mo after the initial vaccination compared with animals receiving a single vaccine dose.
ISSN:1042-7260
1937-2825
DOI:10.1638/03-054