The Puzzle of Contrast Inversion in DNA STM Imaging

DNA has been at the center of an imaging effort since the invention of the scanning tunneling microscope (STM). In some of the STM imaging reports the molecules appeared with negative contrast, i.e., “submerged” under the metal background and darker. We demonstrate the phenomenon of contrast inversi...

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Published in:The journal of physical chemistry. B 2005-08, Vol.109 (30), p.14270-14274
Main Authors: Shapir, Errez, Yi, Juyeon, Cohen, Hezy, Kotlyar, Alexander B, Cuniberti, Gianaurelio, Porath, Danny
Format: Article
Language:English
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DNA - ultrastructure
Microscopy, Scanning Tunneling
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description DNA has been at the center of an imaging effort since the invention of the scanning tunneling microscope (STM). In some of the STM imaging reports the molecules appeared with negative contrast, i.e., “submerged” under the metal background and darker. We demonstrate the phenomenon of contrast inversion in DNA STM imaging by controlled and spontaneous contrast inversions and by the dependence of the DNA apparent height with respect to the surface on the imaging bias voltage. Using these characterizations, we formulate a model explaining the above phenomenon by resonant tunneling through virtual states in the vacuum between the STM tip and the DNA molecule.
doi_str_mv 10.1021/jp052738e
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subjects DNA - ultrastructure
Microscopy, Scanning Tunneling
title The Puzzle of Contrast Inversion in DNA STM Imaging
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