Comparison of Left Ventricular Ejection Fraction and Inducible Ventricular Tachycardia in ST-Elevation Myocardial Infarction Treated by Primary Angioplasty Versus Thrombolysis

Electrophysiologic studies predict the risk for sudden death after myocardial infarction (MI). Although primary angioplasty has become the preferred method of treatment for ST-elevation MI, intravenous thrombolysis remains the first-line treatment in 30% to 70% of cases worldwide. Rates of ventricul...

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Bibliographic Details
Published in:The American journal of cardiology 2008-01, Vol.101 (2), p.153-157
Main Authors: Chong, James J.H., MD, Ganesan, Anand N., MD, PhD, Eipper, Vicki, Kovoor, Pramesh, MD, PhD
Format: Article
Language:English
Subjects:
Angioplasty
Angioplasty, Balloon, Coronary
Biological and medical sciences
Cardiac dysrhythmias
Cardiology
Cardiology. Vascular system
Cardiovascular
Cardiovascular system
Cohort Studies
Coronary heart disease
Coronary vessels
Disease-Free Survival
Diseases of the cardiovascular system
Female
Fibrinolytic Agents - therapeutic use
Heart
Heart attacks
Heart failure
Humans
Investigative techniques of hemodynamics
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Middle Aged
Myocardial Infarction - complications
Myocardial Infarction - drug therapy
Myocardial Infarction - epidemiology
Myocardial Infarction - mortality
Myocardial Infarction - physiopathology
Myocardial Infarction - therapy
New South Wales - epidemiology
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Retrospective Studies
Stroke Volume
Tachycardia, Ventricular - physiopathology
Thrombolytic drugs
Thrombolytic Therapy
Treatment Outcome
Ventricular Dysfunction, Left - physiopathology
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Summary:Electrophysiologic studies predict the risk for sudden death after myocardial infarction (MI). Although primary angioplasty has become the preferred method of treatment for ST-elevation MI, intravenous thrombolysis remains the first-line treatment in 30% to 70% of cases worldwide. Rates of ventricular tachyarrhythmias may vary according to type of reperfusion treatment. This study was undertaken to examine the hypothesis that the left ventricular ejection fraction (LVEF) and rates of inducible ventricular tachycardia may be more favorable in treatment with primary angioplasty rather than thrombolysis. Consecutive patients receiving primary angioplasty (n = 225) or thrombolysis (n = 195) for ST-elevation MI were included. The mean LVEF was 48 ± 12% for the primary angioplasty group and 46 ± 13% for the thrombolysis group (p = 0.30). The proportion of patients with LVEFs
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2007.08.051