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Prediction of Cardiac Death in Hemodialysis Patients by Myocardial Fatty Acid Imaging
Prediction of Cardiac Death in Hemodialysis Patients by Myocardial Fatty Acid Imaging Masato Nishimura, Kazumasa Tsukamoto, Naoyuki Hasebe, Nagara Tamaki, Kenjiro Kikuchi, Toshihiko Ono This prospective cohort study showed that the occurrence of cardiac death among patients on maintenance hemodialys...
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Published in: | Journal of the American College of Cardiology 2008-01, Vol.51 (2), p.139-145 |
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container_title | Journal of the American College of Cardiology |
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creator | Nishimura, Masato, MD, PhD Tsukamoto, Kazumasa, PhD Hasebe, Naoyuki, MD, PhD Tamaki, Nagara, MD, PhD Kikuchi, Kenjiro, MD, PhD Ono, Toshihiko, MD |
description | Prediction of Cardiac Death in Hemodialysis Patients by Myocardial Fatty Acid Imaging Masato Nishimura, Kazumasa Tsukamoto, Naoyuki Hasebe, Nagara Tamaki, Kenjiro Kikuchi, Toshihiko Ono This prospective cohort study showed that the occurrence of cardiac death among patients on maintenance hemodialysis is closely associated with severely abnormal β-methyl iodophenyl-pentadecanoic acid (BMIPP) single-photon emission computed tomography images. Kaplan-Meier survival estimates showed that survival rates worsened with an increasing summed BMIPP score. Highly impaired myocardial fatty acid metabolism can identify groups of hemodialysis patients at high risk for cardiac death. |
doi_str_mv | 10.1016/j.jacc.2007.08.057 |
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Kaplan-Meier survival estimates showed that survival rates worsened with an increasing summed BMIPP score. Highly impaired myocardial fatty acid metabolism can identify groups of hemodialysis patients at high risk for cardiac death.</description><identifier>ISSN: 0735-1097</identifier><identifier>EISSN: 1558-3597</identifier><identifier>DOI: 10.1016/j.jacc.2007.08.057</identifier><identifier>PMID: 18191738</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Aged ; Aged, 80 and over ; Cardiology ; Cardiovascular ; Cardiovascular disease ; Cohort Studies ; Coronary Artery Disease - diagnostic imaging ; Coronary Artery Disease - etiology ; Coronary Artery Disease - mortality ; Death ; Death, Sudden, Cardiac ; Fatty Acids ; Female ; Heart attacks ; Hemodialysis ; Humans ; Internal Medicine ; Kidney Failure, Chronic - diagnosis ; Kidney Failure, Chronic - therapy ; Male ; Medical imaging ; Middle Aged ; Multivariate Analysis ; Predictive Value of Tests ; Probability ; Proportional Hazards Models ; Prospective Studies ; Renal Dialysis - adverse effects ; Renal Dialysis - methods ; Risk Assessment ; ROC Curve ; Sensitivity and Specificity ; Thallium Radioisotopes ; Tomography, Emission-Computed, Single-Photon</subject><ispartof>Journal of the American College of Cardiology, 2008-01, Vol.51 (2), p.139-145</ispartof><rights>American College of Cardiology Foundation</rights><rights>2008 American College of Cardiology Foundation</rights><rights>Copyright Elsevier Limited Jan 15, 2008</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c581t-a595849bf9ed927d20d79a6f84970fc0ba82b63ea08c250b715af183d4b68783</citedby><cites>FETCH-LOGICAL-c581t-a595849bf9ed927d20d79a6f84970fc0ba82b63ea08c250b715af183d4b68783</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18191738$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nishimura, Masato, MD, PhD</creatorcontrib><creatorcontrib>Tsukamoto, Kazumasa, PhD</creatorcontrib><creatorcontrib>Hasebe, Naoyuki, MD, PhD</creatorcontrib><creatorcontrib>Tamaki, Nagara, MD, PhD</creatorcontrib><creatorcontrib>Kikuchi, Kenjiro, MD, PhD</creatorcontrib><creatorcontrib>Ono, Toshihiko, MD</creatorcontrib><title>Prediction of Cardiac Death in Hemodialysis Patients by Myocardial Fatty Acid Imaging</title><title>Journal of the American College of Cardiology</title><addtitle>J Am Coll Cardiol</addtitle><description>Prediction of Cardiac Death in Hemodialysis Patients by Myocardial Fatty Acid Imaging Masato Nishimura, Kazumasa Tsukamoto, Naoyuki Hasebe, Nagara Tamaki, Kenjiro Kikuchi, Toshihiko Ono This prospective cohort study showed that the occurrence of cardiac death among patients on maintenance hemodialysis is closely associated with severely abnormal β-methyl iodophenyl-pentadecanoic acid (BMIPP) single-photon emission computed tomography images. Kaplan-Meier survival estimates showed that survival rates worsened with an increasing summed BMIPP score. Highly impaired myocardial fatty acid metabolism can identify groups of hemodialysis patients at high risk for cardiac death.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Cardiology</subject><subject>Cardiovascular</subject><subject>Cardiovascular disease</subject><subject>Cohort Studies</subject><subject>Coronary Artery Disease - diagnostic imaging</subject><subject>Coronary Artery Disease - etiology</subject><subject>Coronary Artery Disease - mortality</subject><subject>Death</subject><subject>Death, Sudden, Cardiac</subject><subject>Fatty Acids</subject><subject>Female</subject><subject>Heart attacks</subject><subject>Hemodialysis</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Kidney Failure, Chronic - diagnosis</subject><subject>Kidney Failure, Chronic - therapy</subject><subject>Male</subject><subject>Medical imaging</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Predictive Value of Tests</subject><subject>Probability</subject><subject>Proportional Hazards Models</subject><subject>Prospective Studies</subject><subject>Renal Dialysis - adverse effects</subject><subject>Renal Dialysis - methods</subject><subject>Risk Assessment</subject><subject>ROC Curve</subject><subject>Sensitivity and Specificity</subject><subject>Thallium Radioisotopes</subject><subject>Tomography, Emission-Computed, Single-Photon</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><recordid>eNp9kdFqFTEQhoMo9rT6Al5IQPBu18mm2SQgQjm2tlCxYAXvQjbJ1qy7m5rkCPv2ZnsOFHrh1cDwzc_MNwi9IVATIO2HoR60MXUDwGsQNTD-DG0IY6KiTPLnaAOcsoqA5EfoOKUBAFpB5Et0REohnIoN-nETnfUm-zDj0OOtjtZrgz87nX9hP-NLN4XSGZfkE77R2bs5J9wt-OsSzAM84gud84LPjLf4atJ3fr57hV70ekzu9aGeoNuL89vtZXX97cvV9uy6MkyQXGkmmTiVXS-dlQ23DVgudduXHofeQKdF07XUaRCmYdBxwnRPBLWnXSu4oCfo_T72PoY_O5eymnwybhz17MIuKQ5EcsF4Ad89AYewi3NZTREGbaFAyEI1e8rEkFJ0vbqPftJxUQTUalwNajWuVuMKhIKH6LeH6F03Ofs4clBcgI97wBURf72LKpli0RTt0ZmsbPD_z__0ZNyMfvZGj7_d4tLjHSo1CtT39efry4EDpS35Sf8B64qlQA</recordid><startdate>20080115</startdate><enddate>20080115</enddate><creator>Nishimura, Masato, MD, PhD</creator><creator>Tsukamoto, Kazumasa, PhD</creator><creator>Hasebe, Naoyuki, MD, PhD</creator><creator>Tamaki, Nagara, MD, PhD</creator><creator>Kikuchi, Kenjiro, MD, PhD</creator><creator>Ono, Toshihiko, MD</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20080115</creationdate><title>Prediction of Cardiac Death in Hemodialysis Patients by Myocardial Fatty Acid Imaging</title><author>Nishimura, Masato, MD, PhD ; 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subjects | Aged Aged, 80 and over Cardiology Cardiovascular Cardiovascular disease Cohort Studies Coronary Artery Disease - diagnostic imaging Coronary Artery Disease - etiology Coronary Artery Disease - mortality Death Death, Sudden, Cardiac Fatty Acids Female Heart attacks Hemodialysis Humans Internal Medicine Kidney Failure, Chronic - diagnosis Kidney Failure, Chronic - therapy Male Medical imaging Middle Aged Multivariate Analysis Predictive Value of Tests Probability Proportional Hazards Models Prospective Studies Renal Dialysis - adverse effects Renal Dialysis - methods Risk Assessment ROC Curve Sensitivity and Specificity Thallium Radioisotopes Tomography, Emission-Computed, Single-Photon |
title | Prediction of Cardiac Death in Hemodialysis Patients by Myocardial Fatty Acid Imaging |
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