Obstructive sleep apnea syndrome: A potential cause of lower airway obstruction in cystic fibrosis

A six-year-old healthy female with cystic fibrosis (CF) and pancreatic sufficiency presented with cough, weight loss, and lung function decline. Further history suggested obstructive sleep apnea, and nocturnal polysomnography (NPSG) confirmed this. Adenotonsillectomy resulted in resolution of clinic...

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Bibliographic Details
Published in:Sleep medicine 2006, Vol.7 (1), p.73-75
Main Author: Hayes, D.
Format: Article
Language:English
Subjects:
Airway Obstruction - diagnosis
Airway Obstruction - etiology
Airway Obstruction - metabolism
Bronchoscopy - methods
Carbon Dioxide - metabolism
Child
Cystic Fibrosis - complications
Cystic Fibrosis - diagnosis
Female
Fiber Optic Technology - instrumentation
Humans
Polysomnography
Sleep Apnea Syndromes - etiology
Sleep Apnea Syndromes - metabolism
Sleep Apnea, Obstructive - diagnosis
Sleep Apnea, Obstructive - etiology
Sleep Apnea, Obstructive - metabolism
Sleep, REM - physiology
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Summary:A six-year-old healthy female with cystic fibrosis (CF) and pancreatic sufficiency presented with cough, weight loss, and lung function decline. Further history suggested obstructive sleep apnea, and nocturnal polysomnography (NPSG) confirmed this. Adenotonsillectomy resulted in resolution of clinical symptoms with return of normal lung function. This case establishes that obstructive sleep apnea syndrome (OSAS) may be a potential cause of lower airway inflammation and resulting weight loss in the young CF population.
ISSN:1389-9457
1878-5506
DOI:10.1016/j.sleep.2005.07.002