Susceptibilities of Methicillin-Resistant Staphylococcus aureus Isolates to Seven Biocides

Minimum bactericidal concentrations (MBCs) of seven biocides for 42 methicillin-resistant Staphylococcus aureus (MRSA) isolates at 5, 30, or 180 min, for hand scrubs or soaks, isolated in 2003 in Japan were determined. The MBC values of glutaraldehyde, povidone iodine, and ethanol were lower than th...

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Bibliographic Details
Published in:Biological & Pharmaceutical Bulletin 2007, Vol.30(3), pp.585-587
Main Authors: Narui, Koji, Takano, Mitsuo, Noguchi, Norihisa, Sasatsu, Masanori
Format: Article
Language:English
Subjects:
Benzalkonium Compounds - pharmacology
biocide
Chlorhexidine - analogs & derivatives
Chlorhexidine - pharmacology
Disinfectants - pharmacology
Ethanol - pharmacology
exposure time
Female
Glutaral - pharmacology
Hand - microbiology
Hand Disinfection
Humans
Male
Methicillin Resistance
methicillin-resistant Staphylococcus aureus
Microbial Sensitivity Tests - methods
minimum bactericidal concentration
Mucous Membrane - microbiology
Phylogeny
Povidone-Iodine - pharmacology
Sodium Hypochlorite - pharmacology
Staphylococcus aureus - drug effects
Staphylococcus aureus - genetics
Staphylococcus aureus - isolation & purification
Time Factors
Urine - microbiology
user concentration
Wounds and Injuries - microbiology
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Summary:Minimum bactericidal concentrations (MBCs) of seven biocides for 42 methicillin-resistant Staphylococcus aureus (MRSA) isolates at 5, 30, or 180 min, for hand scrubs or soaks, isolated in 2003 in Japan were determined. The MBC values of glutaraldehyde, povidone iodine, and ethanol were lower than the user concentrations in all exposure times. However, at 5 min exposure of sodium hypochlorite, benzalkonium chloride, alkyldiaminoethylglycine hydrochloride, and chlorhexidine digluconate some strains showed higher MBC values than the user concentrations. These results indicated the possibility that MRSA survived under proper user concentration conditions and exposure time.
ISSN:0918-6158
1347-5215
DOI:10.1248/bpb.30.585