Microarray platforms for enzymatic and cell-based assays

This tutorial review introduces the uninitiated to the world of microarrays (or so-called chips) and covers a number of basic concepts such as substrates and surfaces, printing and analysis. It then moves on to look at some newer applications of microarray technology, which include enzyme analysis (...

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Bibliographic Details
Published in:Chemical Society reviews 2007-01, Vol.36 (3), p.449-457
Main Authors: Díaz-Mochón, Juan J, Tourniaire, Guilhem, Bradley, Mark
Format: Article
Language:English
Subjects:
Animals
Cells, Cultured
Enzymes, Immobilized - chemistry
Humans
Microarray Analysis - methods
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Summary:This tutorial review introduces the uninitiated to the world of microarrays (or so-called chips) and covers a number of basic concepts such as substrates and surfaces, printing and analysis. It then moves on to look at some newer applications of microarray technology, which include enzyme analysis (notably kinases and proteases) as well as the growing enchantment with so-called cell-based microarrays that offer a unique approach to high-throughput cellular analysis. Finally, it looks forwards and highlights future possible trends and directions in the microarray arena.
ISSN:0306-0012
1460-4744
DOI:10.1039/b511848b