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Presence of Jaagsiekte sheep retrovirus in tissue sections from human bronchioloalveolar carcinoma depends on patients' geographical origin

Contrasting results for the causative presence of JSRV in subsets of human BACs from different populations using genomic and expression approaches have been reported [1,2,4-7]. Because of the lack of confirmatory studies, we here tried to further assess the role of the genomic integration of JSRV-re...

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Published in:	Human pathology 2008-02, Vol.39 (2), p.303-304
Main Authors:	Rocca, Stefano, PhD, Sanna, Maria Paola, PhD, Leoni, Antonio, PhD, Cossu, Antonio, MD, Lissia, Amelia, MD, Tanda, Francesco, MD, Satta, Maria Paola, Palmieri, Giuseppe, MD
Format:	Article
Language:	English
Subjects:	Adenocarcinoma, Bronchiolo-Alveolar - epidemiology Adenocarcinoma, Bronchiolo-Alveolar - genetics Adenocarcinoma, Bronchiolo-Alveolar - virology Animals Base Sequence Deoxyribonucleic acid DNA DNA, Neoplasm - analysis DNA, Viral - analysis Genes Humans Italy - epidemiology Jaagsiekte sheep retrovirus - genetics Jaagsiekte sheep retrovirus - isolation & purification Lung Neoplasms - epidemiology Lung Neoplasms - genetics Lung Neoplasms - virology Medical research Molecular Sequence Data Pathogenesis Pathology Pulmonary Adenomatosis, Ovine - epidemiology Pulmonary Adenomatosis, Ovine - genetics Pulmonary Adenomatosis, Ovine - virology Sequence Analysis, DNA Sheep
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description	Contrasting results for the causative presence of JSRV in subsets of human BACs from different populations using genomic and expression approaches have been reported [1,2,4-7]. Because of the lack of confirmatory studies, we here tried to further assess the role of the genomic integration of JSRV-related DNA sequences into the BAC pathogenesis by analyzing a series of tumor and normal tissues from different geographical areas.
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subjects	Adenocarcinoma, Bronchiolo-Alveolar - epidemiology Adenocarcinoma, Bronchiolo-Alveolar - genetics Adenocarcinoma, Bronchiolo-Alveolar - virology Animals Base Sequence Deoxyribonucleic acid DNA DNA, Neoplasm - analysis DNA, Viral - analysis Genes Humans Italy - epidemiology Jaagsiekte sheep retrovirus - genetics Jaagsiekte sheep retrovirus - isolation & purification Lung Neoplasms - epidemiology Lung Neoplasms - genetics Lung Neoplasms - virology Medical research Molecular Sequence Data Pathogenesis Pathology Pulmonary Adenomatosis, Ovine - epidemiology Pulmonary Adenomatosis, Ovine - genetics Pulmonary Adenomatosis, Ovine - virology Sequence Analysis, DNA Sheep
title	Presence of Jaagsiekte sheep retrovirus in tissue sections from human bronchioloalveolar carcinoma depends on patients' geographical origin
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