Concomitant cardiovascular conditions in intestinal illness

• Published in: Der Internist (Berlin) 2007-03, Vol.48 (3), p.290-296
• Main Authors: Rellecke, P, Strauer, B E
• Format: Article
• Language: ger
• Subjects: Cardiovascular Diseases - diagnosis; Colitis, Ischemic - diagnosis; Colitis, Ulcerative - diagnosis; Colonic Neoplasms - diagnosis; Comorbidity; Coronary Disease - diagnosis; Crohn Disease - diagnosis; Heart Neoplasms - diagnosis; Heart Neoplasms - secondary; Humans; Takayasu Arteritis - diagnosis; Thromboembolism - diagnosis; Vasculitis - diagnosis
• ISSN: 0020-9554
• DOI: 10.1007/s00108-006-1761-1

Vascular diseases are not encountered very often in gastroenterology, though in cases of ischemic colitis a coronary heart disease is often present. In addition, heart diseases such as coronary heart disease, atrial fibrillation, and congestive heart failure are important risk factors for ischemic colitis and should be treated to avoid further ischemic episodes of the gut. The most common extraintestinal manifestations of Crohn's disease and ulcerative colitis are observed in the eye, on the skin, and in the liver region. Involvement of the cardiovascular system does not seem to be very common, though systematic epidemiological data on the significance of these extraintestinal complications--which certainly influence the prognosis--are lacking. Other patients with Crohn's disease or ulcerative colitis suffer from vasculitis, which reflects a further manifestation of inflammatory diseases affecting the cardiovascular system. Another important complication is activation of coagulationfactors, especially during active flare-up of intestinal disease; this can result in thromboembolic events. Systematic studies or investigations on the epidemiology of cardiovascular complications are still lacking, so that an overview of the published data is given. Metastatic tumors of the heart are rare, but there are case reports of cardiac metastases in patients with carcinomas of the colon. Carcinoid heart syndrome, another cardial complication of malignant disease, can prejudice the prognosis of patients with neuroendocrine tumors of the gastrointestinal tract.