Effects of Valsartan or Amlodipine Alone or in Combination on Plasma Catecholamine Levels at Rest and During Standing in Hypertensive Patients

To compare the effects of valsartan and amlodipine alone or in combination on plasma norepinephrine (NE) at rest and standing for 10 minutes in patients with hypertension, 47 patients with a sitting diastolic blood pressure (BP) (DBP) >95 mm Hg and 90 mm Hg (nonresponders) received combination th...

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Bibliographic Details
Published in:The journal of clinical hypertension (Greenwich, Conn.) Conn.), 2007-03, Vol.9 (3), p.168-178
Main Authors: Champlain, Jacques de, Karas, Maria, Assouline, Linda, Nadeau, Reginald, LeBlanc, A. Robert, Dubé, Bruno, Larochelle, Pierre
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Amlodipine - therapeutic use
Angiotensin II Type 1 Receptor Blockers
Antihypertensive Agents - therapeutic use
Biomarkers - blood
Blood Pressure - drug effects
Catecholamines - blood
Chromatography, High Pressure Liquid
Drug Therapy, Combination
Female
Heart Rate - drug effects
Heart Rate - physiology
Humans
Hypertension - blood
Hypertension - drug therapy
Hypertension - physiopathology
Male
Middle Aged
Posture - physiology
Rest - physiology
Tetrazoles - therapeutic use
Treatment Outcome
Valine - analogs & derivatives
Valine - therapeutic use
Valsartan
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Summary:To compare the effects of valsartan and amlodipine alone or in combination on plasma norepinephrine (NE) at rest and standing for 10 minutes in patients with hypertension, 47 patients with a sitting diastolic blood pressure (BP) (DBP) >95 mm Hg and 90 mm Hg (nonresponders) received combination therapy with the other drug, whereas patients with a DBP
ISSN:1524-6175
1751-7176
DOI:10.1111/j.1524-6175.2007.05938.x