Successful dexamethasone pulse therapy for widespread erosive perianal lichen planus

A 70-year-old man presented with a 6-month history of extensive, progressive perianal erosions. In addition, he had white reticulate striae and small erosions on the penis. The clinical diagnosis of erosive lichen planus was confirmed histologically. After several topical approaches failed and his s...

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Bibliographic Details
Published in:Hautarzt 2007-03, Vol.58 (3), p.241-245
Main Authors: Weyandt, G H, Vetter-Kauczok, C-S, Becker, J C, Bröcker, E-B, Hamm, H
Format: Article
Language:ger
Subjects:
Aged
Anal Canal - drug effects
Anti-Inflammatory Agents - administration & dosage
Dexamethasone - administration & dosage
Humans
Lichen Planus - diagnosis
Lichen Planus - drug therapy
Male
Pulse Therapy, Drug - methods
Treatment Outcome
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Summary:A 70-year-old man presented with a 6-month history of extensive, progressive perianal erosions. In addition, he had white reticulate striae and small erosions on the penis. The clinical diagnosis of erosive lichen planus was confirmed histologically. After several topical approaches failed and his ss-blocker was stooped, 3 pulses of dexamethasone (100 mg dexamethasone i.v. on 3 consecutive days every 4 weeks) led to complete and long-lasting remission.
ISSN:0017-8470
DOI:10.1007/s00105-006-1188-6