A profile of neuropsychiatric problems and their relationship to quality of life for Parkinson's disease patients without dementia

Abstract Neuropsychiatric problems are common in Parkinson's disease (PD) but there is little information regarding how they impact on quality of life. PD patients without dementia (49) were assessed for low mood/depression, fatigue, apathy, sleep problems and hallucinations. Measures of qualit...

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Bibliographic Details
Published in:Parkinsonism & related disorders 2008-01, Vol.14 (1), p.37-42
Main Authors: McKinlay, A, Grace, R.C, Dalrymple-Alford, J.C, Anderson, T, Fink, J, Roger, D
Format: Article
Language:English
Subjects:
Anxiety
Apathy
Dementia
Depression
Depression - etiology
Fatigue
Fatigue - etiology
Hallucinations - etiology
Humans
Neurology
Neuropsychological Tests
Parkinson Disease - complications
Parkinson Disease - psychology
Parkinson's disease
Quality of Life
Quality of life-PDQ
Sleep Wake Disorders - etiology
Tremor - etiology
Tremor - psychology
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Summary:Abstract Neuropsychiatric problems are common in Parkinson's disease (PD) but there is little information regarding how they impact on quality of life. PD patients without dementia (49) were assessed for low mood/depression, fatigue, apathy, sleep problems and hallucinations. Measures of quality of life and motor function were also obtained. Over 77% of the patients reported symptoms consistent with one or more neuropsychiatric problems. Low mood/depression, anxiety and the presence of hallucinations predicted poorer quality of life after controlling for motor symptoms. Additional to the motor symptoms, we found that specific neuropsychiatric problems may impact on quality of life for PD patients.
ISSN:1353-8020
1873-5126
DOI:10.1016/j.parkreldis.2007.05.009