Multifocal posterior uveitis in Crohn's disease

To report a case of rare posterior eye manifestation of Crohn's disease preceding recurrence of inflammatory bowel disease. Case report with ophthalmoscopic findings, fluorescein/indocyanin green angiograms, automated perimetry and multifocal-ERG. The perimetry revealed absolute and relative sc...

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Bibliographic Details
Published in:Graefe's archive for clinical and experimental ophthalmology 2007-03, Vol.245 (3), p.457-459
Main Authors: Tappeiner, C, Dohrmann, J, Spital, G, Heiligenhaus, A
Format: Article
Language:English
Subjects:
Adult
Coloring Agents
Crohn Disease - complications
Crohn Disease - drug therapy
Electroretinography
Female
Fluorescein Angiography
Glucocorticoids - therapeutic use
Humans
Indocyanine Green
Prednisolone - therapeutic use
Scotoma - etiology
Uveitis, Posterior - diagnosis
Uveitis, Posterior - drug therapy
Uveitis, Posterior - etiology
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Summary:To report a case of rare posterior eye manifestation of Crohn's disease preceding recurrence of inflammatory bowel disease. Case report with ophthalmoscopic findings, fluorescein/indocyanin green angiograms, automated perimetry and multifocal-ERG. The perimetry revealed absolute and relative scotomas corresponding to multifocal inflammatory lesions in the retina and choroid, reduced a/b amplitudes in multifocal-ERG and hypofluorescent dots in angiography. Under oral prednisolone visual defects, ophthalmoscopic and angiographic findings resolved, while a/b amplitudes remained mildly reduced. The ocular changes occurred without systemic hypertension and were followed by a new episode of intestinal symptoms. Multifocal inflammatory lesions in the retina and choroid in patients with Crohn's disease may occur and may precede a recurrent intestinal episode. Crohn's patients should be carefully followed up in collaboration with internal medicine specialists.
ISSN:0721-832X
1435-702X
DOI:10.1007/s00417-006-0363-x