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Genotyping of Panamanian Trypanosoma cruzi stocks using the calmodulin 3'UTR polymorphisms

Mutations in the 3' untranslated region of calmodulin gene have recently been reported to be specific to different Trypanosoma cruzi lineages. In the present report, this molecular marker was used to genotype 24 T. cruzi isolates from humans and vectors from different endemic areas in Panama. T...

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Published in:Parasitology research (1987) 2008-02, Vol.102 (3), p.523-526
Main Authors: Brandao, Adeilton, Samudio, Franklyn, Fernandes, Octavio, Calzada, Jose E, Sousa, Octavio E
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container_title Parasitology research (1987)
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creator Brandao, Adeilton
Samudio, Franklyn
Fernandes, Octavio
Calzada, Jose E
Sousa, Octavio E
description Mutations in the 3' untranslated region of calmodulin gene have recently been reported to be specific to different Trypanosoma cruzi lineages. In the present report, this molecular marker was used to genotype 24 T. cruzi isolates from humans and vectors from different endemic areas in Panama. The finding of solely T. cruzi I genotype might explain the low morbidity of Chagas' disease in the region when compared to other countries in Latin America.
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ispartof Parasitology research (1987), 2008-02, Vol.102 (3), p.523-526
issn 0932-0113
1432-1955
language eng
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subjects 3' Untranslated Regions - genetics
Animals
Base Sequence
Biological and medical sciences
Calmodulin - genetics
Conserved Sequence
Fundamental and applied biological sciences. Psychology
General aspects
General aspects and techniques. Study of several systematic groups. Models
Genotype
Invertebrates
Panama
Polymorphism, Genetic
Protozoan Proteins - genetics
Sequence Alignment
Sequence Homology, Nucleic Acid
Species Specificity
Trypanosoma cruzi - genetics
Trypanosoma cruzi - isolation & purification
title Genotyping of Panamanian Trypanosoma cruzi stocks using the calmodulin 3'UTR polymorphisms
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