Review of the economic and quality-of-life burden of cervical human papillomavirus disease

Objective The purpose of this study was to conduct a systematic literature review on the economic burden and health-related quality-of-life impact of cervical human papillomavirus disease. Study Design A systematic review of cost-of-illness studies and health-related quality-of-life studies was cond...

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Bibliographic Details
Published in:American journal of obstetrics and gynecology 2007-03, Vol.196 (3), p.206-212
Main Authors: Fleurence, Rachael L., PhD, Dixon, Julia M., BS, Milanova, Tsveta F., MSc, Beusterien, Kathleen M., MPH
Format: Article
Language:English
Subjects:
Biological and medical sciences
cervical cancer
Cost of Illness
economics
Female
Female genital diseases
Gynecology. Andrology. Obstetrics
human papillomavirus
Humans
Medical sciences
Obstetrics and Gynecology
Papillomavirus Infections - economics
Quality of Life
Tumors
Uterine Cervical Neoplasms - economics
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Summary:Objective The purpose of this study was to conduct a systematic literature review on the economic burden and health-related quality-of-life impact of cervical human papillomavirus disease. Study Design A systematic review of cost-of-illness studies and health-related quality-of-life studies was conducted. PubMed, Embase, and PsycINFO databases were searched with the use of predefined terms. Results Nine economic and 24 quality-of-life studies were identified. The annual health care costs of human papillomavirus–related conditions in the United States range from $2.25-$4.6 billion (2005 US dollars). The burden of human papillomavirus is second only to human immunodeficiency virus among sexually transmitted diseases. Health-related quality-of-life areas that are impacted substantially by human papillomavirus include emotional, social, and sexual functioning. Conclusion The economic and quality-of-life burden of cervical human papillomavirus disease is significant and highlights the need for treatment and prevention options for this condition.
ISSN:0002-9378
1097-6868
DOI:10.1016/j.ajog.2007.01.028