A note on difficult structure alignment problems

Progress in structural biology depends on several key technologies. In particular tools for alignment and superposition of protein structures are indispensable. Here we describe the use of the TopMatch web service, an effective computational tool for protein structure alignment, for the visualizatio...

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Bibliographic Details
Published in:Bioinformatics 2008-02, Vol.24 (3), p.426-427
Main Authors: Sippl, Manfred J., Wiederstein, Markus
Format: Article
Language:English
Subjects:
Algorithms
Amino Acid Sequence
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
General aspects
Internet
Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects)
Molecular Sequence Data
Proteins - chemistry
Sequence Alignment - methods
Sequence Analysis, Protein - methods
Software
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Summary:Progress in structural biology depends on several key technologies. In particular tools for alignment and superposition of protein structures are indispensable. Here we describe the use of the TopMatch web service, an effective computational tool for protein structure alignment, for the visualization of structural similarities, and for highlighting relationships found in protein classifications. We provide several instructive examples. Availability: TopMatch is available as a public web service at http://services.came.sbg.ac.at Contact: sippl@came.sbg.ac.at
ISSN:1367-4803
1460-2059
1367-4811
DOI:10.1093/bioinformatics/btm622